New antibodies found for gluten sensitivity

How many people here don’t eat gluten?

People can have issues with gluten for different reasons. Gluten is most dangerous for people who have celiac disease (an autoimmune response that destroys the intestinal lining). Wheat allergy is another reason to avoid gluten because wheat is the most common food source. .

There are tests to confirm whether a person has celiac disease or wheat allergy, so we want to check for these possibilities in anybody we suspect may not do well with gluten.

“New research suggests that we MAY be able to test for NCGS!”

But there’s another category of people who don’t feel well when they eat gluten. They might have digestive problems or any number of symptoms that come on after eating gluten—but no medical tests can figure out why. We call this non-celiac gluten sensitivity (NCGS).

New research suggests that we MAY be able to test for NCGS!

Researchers analyzed blood from 40 patients with celiac disease, 80 with NCGS, and 40 with no sensitivity to gluten. Here’s what they found:

👉 Those with celiac disease produced high levels of anti-gliadin IgG antibodies of types IgG1 and IgG3 (with some elevation of IgG2).
👉 Those with NCGS produced elevated levels of IgG4 and IgG2

This new information suggests that people who have NCGS are mounting an immune reaction to gluten that is different from the immune reaction of celiac disease but still real and detectable!

Before we get too excited and start running in for blood tests, let’s be clear. This is very early research and only observational. It cannot prove a cause-and-effect, so there’s more we need to know.

But it’s exciting to see tangible evidence that NCGS is NOT made up and not just in your head. Gluten can cause subtle problems that are finally being detected by science.

What can you do if you suspect you may have a gluten sensitivity or allergy? Talk to a doctor or nutritionist! Try removing gluten from your diet for a few weeks then add it back in slowly and watch for a reaction. The reaction can be immediate or you could notice a reaction for up to 72 hours after eating gluten. Read ingredient labels! Arm yourself with information! Gluten can be hidden in packaged foods, spices, medications, and personal care products.

A reaction to a food that your body does not tolerate can severely affect your gut. Healing the gut and helping you navigate a life without gluten is where I can help! 🙋‍♀️ Reach out with any questions you may have regarding testing, recommendations for foods to eat or gut healing. 


Uhde M, Caio G, De Giorgio R, Green PH, Volta U, Alaedini A. Subclass Profile of IgG Antibody Response to Gluten Differentiates Non-Celiac Gluten Sensitivity from Celiac Disease. Gastroenterology. 2020;